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"In recent years, the studies of the effects of drugs on the behavior of animals have been playing an increasingly important role. Animal studies have been an advantage over studies with human subjects because better control of experimental variables and a possibility of using a wider range of the doses. It is also permissible to administer toxix compounds to animals. One can interfere surgically with various parts of the central nervous system while investigating the effects of the drugs. The whole field of comparative psychopharmacology has been recently reviewed"
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