"I have long known that it is part of God’s plan for me to spend a little time with each of the most stupid people on earth, and Mary Ellen was proof that even in the Appalachian woods I would not be spared. It became evident from the first moment that she was a rarity."

“The Smokies seem to be in the process of losing most of their mussels. The National Park Service actually has something of a tradition of making things extinct. Bryce Canyon National Park is perhaps the most interesting—certainly the most striking—example. It was founded in 1923 and in less than half a century under the Park Service’s stewardship lost seven species of mammal—the white-tailed jackrabbit, prairie dog, pronghorn antelope, flying squirrel, beaver, red fox, and spotted skunk. Quite an achievement when you consider that these animals had survived in Bryce Canyon for tens of millions of years before the Park Service took an interest in them. Altogether, forty-two species of mammal have disappeared from America’s national parks this century.”

“Consider the fact that for 3.8 billion years, a period of time older than the Earth's mountains and rivers and oceans, every one of your forebears on both sides has been attractive enough to find a mate, healthy enough to reproduce, and sufficiently blessed by fate and circumstances to live long enough to do so. Not one of your pertinent ancestors was squashed, devoured, drowned, starved, stranded, stuck fast, untimely wounded, or otherwise deflected from its life's quest of delivering a tiny charge of genetic material to the right partner at the right moment in order to perpetuate the only possible sequence of hereditary combinations that could result -- eventually, astoundingly, and all too briefly -- in you.”

“Normally, your wife can hear things that no one else on earth can hear. She can hear a dab of jam fall onto a carpet two rooms away. She can hear spilled coffee being furtively mopped up with a good bathtowel. She can hear dirt being tracked across a clean floor. She can hear you just thinking about doing something you shouldn't do. But get yourself stuck in a loft hatch and suddenly it is as if she has been placed in a soundproof chamber.”

“Bryson. You’ve got three kinds of chromosomes: X, Y and fuck-head. - Katz”

“It is natural human impulse to think of evolution as a long chain of improvements, of a never-ending advance towards largeness and complexity — in a word, towards us. We flatter ourselves. Most of the real diversity in evolution has been small-scale. We large things are just flukes — an interesting side branch.”

“America is an outstandingly dangerous place. Consider this: every year in New Hampshire a dozen or more people are killed crashing their cars into moose. Now correct me if I am wrong, but this is not something that is likely to happen to you on the way home from Sainsbury's.”