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"The significant problems of living organisms are seldom those in which one can rigidly maintain constant all but two variables. Living things are more likely to present situations in which a half-dozen, or even several dozen quantities are all varying simultaneously, and in subtly interconnected ways. Often they present situations in which the essentially important quantities are either non-quantitative, or have at any rate eluded identification or measurement up to the moment. Thus biological and medical problems often involve the consideration of a most complexly organized whole."
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"he queen spoke to myself ... I asked leave to speak my mind plainly; which she granted: I said, any treaty by which Spain and the West Indies were left to king Philip, must in a little while deliver u…"
— Gilbert Burnet
Religion1643–1715
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