"A poet once said, "The whole universe is in a glass of wine." We will probably never know in what sense he meant that, for poets do not write to be understood. But it is true that if we look at a glass of wine closely enough we see the entire universe. There are the things of physics: the twisting liquid which evaporates depending on the wind and weather, the reflections in the glass, and our imagination adds the atoms. The glass is a distillation of the Earth's rocks, and in its composition we see the secrets of the universe's age, and the evolution of stars. What strange arrays of chemicals are in the wine? How did they come to be? There are the ferments, the enzymes, the substrates, and the products. There in wine is found the great generalization: all life is fermentation. Nobody can discover the chemistry of wine without discovering, as did Louis Pasteur, the cause of much disease. How vivid is the claret, pressing its existence into the consciousness that watches it! If our small minds, for some convenience, divide this glass of wine, this universe, into parts — physics, biology, geology, astronomy, psychology, and so on — remember that nature does not know it! So let us put it all back together, not forgetting ultimately what it is for. Let it give us one more final pleasure: drink it and forget it all!"

“All right. I already see you turning off. I can see you say you don't understand me. You can't understand that it could be chance. "I don't like it!" Tough! I don't like it either, but that's the way it is! OK? I don't understand it either. ..."It must be that Nature knows that it's going to go up or down." No, it must not be that nature knows! We are not to tell Nature what she's gotta be! That's what we found out. Every time we take a guess as how she's got to be, and go and measure... She's clever. She's always got better imagination than we have, and she finds a cleverer way to do it than we have thought of. And in this particular case, the clever way to do it is by probability, by odds. ...[L]ight works by probability.”

“The first principle is that you must not fool yourself — and you are the easiest person to fool.”

“We've learned from experience that the truth will out. Other experimenters will repeat your experiment and find out whether you were wrong or right. Nature's phenomena will agree or they'll disagree with your theory. And, although you may gain some temporary fame and excitement, you will not gain a good reputation as a scientist if you haven't tried to be very careful in this kind of work. And it's this type of integrity, this kind of care not to fool yourself, that is missing to a large extent in much of the research in cargo cult science.”

“I, therefore, did learn a lesson: The female mind is capable of understanding analytic geometry. Those people who have for years been insisting (in the face of all obvious evidence to the contrary) that the male and female are equally capable of rational thought may have something. The difficulty may just be that we have never yet discovered a way to communicate with the female mind. If it is done in the right way, you may be able to get something out of it.”

“Hell, if I could explain it to the average person, it wouldn't have been worth the Nobel prize.”

“The real problem in speech is not precise language. The problem is clear language. The desire is to have the idea clearly communicated to the other person. It is only necessary to be precise when there is some doubt as to the meaning of a phrase, and then the precision should be put in the place where the doubt exists. It is really quite impossible to say anything with absolute precision, unless that thing is so abstracted from the real world as to not represent any real thing.Pure mathematics is just such an abstraction from the real world, and pure mathematics does have a special precise language for dealing with its own special and technical subjects. But this precise language is not precise in any sense if you deal with real objects of the world, and it is only pedantic and quite confusing to use it unless there are some special subtleties which have to be carefully distinguished.”