"If you told me I was going to live to 240, I would take 10 years off and try and act. I don't have that kind of time, so I'd much rather stick to playing guitar."

“I won't ever get on stage at a comedy club when people know about it.”

“I was smart enough to know it would probably make me a salable item for the paparazzi. I knew I’d have to move to a home that had a gate. But that pearl of possibility that lives in your heart when you meet somebody you want to know more about has such a different molecular density than everything else that you have to pursue it.”

“It wasn’t as direct as me saying “I now make the choice to bring the paparazzi into my life.” I really said, “I now make the choice to sleep with Jessica Simpson.” That was stronger than my desire to stay out of the paparazzi’s eye.”

“I am not in Us Weekly. I'd have to be going out with someone who is in there to be in there myself.”

“Square pegged", Mayer's first feature article in 2001, from Creative Loafing”

“I never worked with T.I. Here's the back story to that Wikipedia nugget: I was a guest on TRL and happened to get my hands on the list of goofy, un Andrew-Miller-like questions I was going to be asked before I walked on set. One of the questions was "Who do you like more, T.I. or ?" So I snuck to the bathroom and searched "T.I." on my Blackberry. I memorized as much information as I could and then announced that we were working together.”