"The universe of all things that exist may be understood as a universe of systems where a system is defined as any set of related and interacting elements. This concept is primitive and powerful and has been used increasingly over the last half-century to organize knowledge in virtually all domains of interest to investigators. As human inventions and social interactions grow more complex, general conceptual frameworks that integrate knowledge among different disciplines studying those emerging systems grow more important. Living systems theory instructs integrative research among biological and social sciences and related academic disciplines."

“The structure of a system is the arrangement of its subsystems and components in three-dimensional space at a given moment of time. This always changes over time. It may remain relatively fixed for a long period or it may change from moment to moment, depending upon the characteristics of the process in the system. This process halted at any given moment, as when motion is frozen by a high-speed photograph, reveals the three-dimensional spatial arrangement of the system's components as of that instant.”

“The term system has a number of meanings. There are systems of numbers and of equations, systems of value and of thought, systems of law, solar systems, organic systems, management systems, command and control systems, electronic systems, even the Union Pacific Railroad system. The meanings of "system" are often confused. The most general, however, is: A system is a set of interacting units with relationships among them. The word "set" implies that the units have some common properties. These common properties are essential if the units are to interact or have relationships. The state of each unit is constrained by, conditioned by, or dependent on the state of other units. The units are coupled. Moreover, there is at least one measure of the sum of its units which is larger than the sum of that measure of its units.”

“The most general form of systems theory is a set of logical or mathematical statements about all conceptual systems. A subset of this concerns all concrete systems. A subsubset concerns the very special and very important living systems, i.e., general living systems theory.”

“My analysis of living systems uses concepts of thermodynamics, information theory, cybernetics, and systems engineering, as well as the classical concepts appropriate to each level. The purpose is to produce a description of living structure and process in terms of input and output, flows through systems, steady states, and feedbacks, which will clarify and unify the facts of life.”

“In such fundamental considerations it would be surprising if many new concepts appear, for countless good minds have worked long on these matters over many years. Indeed, new original ideas should at first be suspect, though if they withstand examination they should be welcomed. My intent is not to create a new school or art form but to discern the pattern of a mosaic which lies hidden in the cluttered, colored marble chips of today's empirical facts.”

“Osgood's semantic space as determined by subjects' ratings of words on the semantic differential test.”