"The skein of human continuity must often become this tenuous across the centuries , but the circle remains unbroken if I can touch the ink of Lavoisier's own name, written by his own hand. A candle of light, nurtured by the oxygen of his greatest discovery, never burns out if we cherish the intellectual heritage of such unfractured filiation across the ages. We may also wish to contemplate the genuine physical thread of nucleic acid that ties each of us to the common bacterial ancestor of all living creatures, born on Lavoisier's ancienne terre more than 3.5 billion years ago—and never since disrupted, not for one moment, not for one generation. Such a legacy must be worth preserving from all the guillotines of our folly."

“Knowledge and wonder are the dyad of our worthy lives as intellectual beings. Voyager did wonders for our knowledge, but performed just as mightily in the service of wonder—and the two elements are complementary, not independent or opposed. The thought fills me with awe—a mechanical contraption that could fit in the back of a pickup truck, traveling through space for twelve years, dodging around four giant bodies and their associated moons, and finally sending exquisite photos across more than four light-hours of space from the farthest planet in our solar system.”

“I believe that we can still have a genre of scientific books suitable for and accessible alike to professionals and interested laypeople. The concepts of science, in all their richness and ambiguity, can be presented without any compromise, without any simplification counting as distortion, in language accessible to all intelligent people. I hope that this book can be read with profit both in seminars for graduate students and—if the movie stinks and you forgot your sleeping pills—on the businessman's special to Tokyo.”

“In all my years of teaching with Steve, I have never seen him flustered or at a loss for words—except once. In our course entitled "Thinking About Thinking," he had been presenting a lecture on the randomness of nature and referred to Einstein's famous dictum "I shall never believe that God plays dice with the world." I responded by walking up to the blackboard and writing, "Gould or God?" I then argued that if God does not play dice with the universe, as Einstein said, and if the universe is as random as the throws of honest dice, as Gould says, then there could not be a God. Hence, Gould or God? Then I sat down, leaving it to Steve to answer the challenge. He stood up and looked at the words on the blackboard. He hesitated, gathered his thoughts, and then launched into a defense of God so brilliant that even William Jennings Bryan would have been proud. It was then that I realized what a great lawyer Gould would make. As for God... ?”

“Evolution is an obstacle course not a freeway; the correct analogue for long-term success is a distant punt receiver evading legions of would-be tacklers in an oddly zigzagged path toward a goal, not a horse thundering down the flat.”

“I can only look from the outside . I am stuck with a panoply of ineluctably indirect methods - some very sophisticated to be sure. I can atomize, experiment, and infer. I can record reams of data about behaviors and responses. But if I could be a beetle or a bacillus for that one precious minute - and live to tell the tale in perfect memory - then I might truly fulfill Darwin's dictum penned into an early notebook containing the first full flowering of his evolutionary ideas during the late 1830's: "He who understands the baboon would do more towards metaphysics than Locke.”

“I relish the fact that we New Yorkers talk funny, and that art deco skyscrapers symbolize our city. But we must set boundaries to this love of variety. I accept the need, even the blessings, of standardization in practical matters: we require a worldwide telephone dialing system and a network of national highways . We need domains of standardization, and realms of regionalism, each in its appropriate place, and linked in mutual respect and recognition. I accept and even want McDonalds at the highway interchange—but not in my little neighborhood of ethnic restaurants, and not next to the Corn Palace in Mitchell, South Dakota.”