"Ted Seabrooke, my wrestling coach, had a kind of Nietzschean effect on me in terms of not just his estimation of my limited abilities, but his decidedly philosophical stance about how to conduct your life, what you should do to compensate for your limitations. This was essential to me, both as a student—and not a good one—and as a wrestler who was not a natural athlete but who had found something he loved."

“I write repeatedly—against my will—of those things I fear most happening. Losing a loved one, losing a parent, losing a child. I'm in terror of losing a child. It's never happened to me, but I am clearly compelled to write about it over and over again, and in a way I think, psychologically at least, this says more about me autobiographically as a novelist than the fact that Danny Angel goes to the Iowa Writers Workshop and has Kurt Vonnegut as a teacher, which I also did.”

“You can't learn everything you need to know legally.”

“A reader told me recently, in London, said that 'well, I read that you write the last sentence first, so I always read your last sentence first.' And I said, 'oh, no, you're not supposed to do that.'”

“John Irving interviewed by Jonathan Derbyshire in New Statesman about his book Last Night in Twisted River”

“I can't imagine what the first sentence is, I can't imagine where I want the reader to enter the story, if I don't know where the reader is going to leave the story. So once I know what the last thing the reader hears is, I can work my way backward, like following a roadmap in reverse.”

“Sigmund Freud was a novelist with a scientific background. He just didn’t know he was a novelist. All those damn psychiatrists after him, they didn’t know he was a novelist either.”