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"What we know of physical and biological science makes existence of God less probable than the existence of Santa Claus. And the parts of physics that rule out God are not themselves open to much doubt. There is no chance that they will be revised by anything yet to be discovered. To be sure, there will be revolutionary developments in science. Superstring theory may give way to quantum-loop gravity; exceptions to the genetic code may be discovered; some unique function of consciousness may be identified. But there are some things that won't happen. Purposes and designs will never have a role in physics and biology. Perpetual motion machines and other violations of the laws of thermodynamics won't arise, not even if there turns out to be such a thing as cold fusion."
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