"What I've learned in my life, it's a very interesting social study for me, to go back and forth between being the guy at home and being the guy on the road and being the guy in studio and being the guy in the interview. The environment around you has so much to do with your character, and when I'm home, my character really changes quite a bit. I become very domesticated, it becomes riding my bike, and the music thing — the music thing doesn't leave but it's kind of less put upon me by other people as a musician."

“If you told me I was going to live to 240, I would take 10 years off and try and act. I don't have that kind of time, so I'd much rather stick to playing guitar.”

“I won't ever get on stage at a comedy club when people know about it.”

“I was smart enough to know it would probably make me a salable item for the paparazzi. I knew I’d have to move to a home that had a gate. But that pearl of possibility that lives in your heart when you meet somebody you want to know more about has such a different molecular density than everything else that you have to pursue it.”

“It wasn’t as direct as me saying “I now make the choice to bring the paparazzi into my life.” I really said, “I now make the choice to sleep with Jessica Simpson.” That was stronger than my desire to stay out of the paparazzi’s eye.”

“I am not in Us Weekly. I'd have to be going out with someone who is in there to be in there myself.”

“Square pegged", Mayer's first feature article in 2001, from Creative Loafing”