"When, in the autumn of 1947, I was fired from the first and only job I have ever held, I wanted one thing out of life: to become a writer. I left my position as manuscript reader at the McGraw-Hill Book Company with no regrets; the job had been onerous and boring. It did not occur to me that there would be many difficulties to impede my ambition; in fact, the job itself had been an impediment. All I knew was that I burned to write a novel and I could not have cared less that my bank account was close to zero, with no replenishment in sight. At the age of twenty-two I had such pure hopes in my ability to write not just a respectable first novel, but a novel that would be completely out of the ordinary, that when I left the McGraw-Hill Building for the last time I felt the exultancy of a man just released from slavery and ready to set the universe on fire."

“For in virtually any other serious sickness, a patient who felt similar devastation would be lying flat in bed, possibly sedated and hooked up to the tubes and wires of life-support systems, but at the very least in a posture of repose and in an isolated setting. His invalidism would be necessary, unquestioned and honorably attained. However, the sufferer from depression has no such option and therefore finds himself, like a walking casualty of war, thrust into the most intolerable social and family situations. There he must, despite the anguish devouring his brain, present a face approximating the one that is associated with ordinary events and companionship. He must try to utter small talk, and be responsive to questions, and knowingly nod and frown and, God help him, even smile.”

“Someday I will understand Auschwitz. This was a brave statement but innocently absurd. No one will ever understand Auschwitz.”

“For those who have dwelt in depression’s dark wood, and known its inexplicable agony, their return from the abyss is not unlike the ascent of the poet, trudging upward and upward out of hell’s black depths and at last emerging into what he saw as “the shining world.” There, whoever has been restored to health has almost always been restored to the capacity for serenity and joy, and this may be indemnity enough for having endured the despair beyond despair.”

“Tidewater traumas profile by James Campbell at The Guardian Unlimited website .”

““Surely mankind has yet to be born. Surely this is true! For only something blind and uncomprehending could exist in such a mean conjunction with its own flesh, its own kind. How else account for such faltering, clumsy, hateful cruelty? Even the possums and the skunks know better! Even the weasels and the meadow mice have a natural regard for their own blood and kin. Only the insects are low enough to do the low things that people do — like those ants that swarm on poplars in the summertime, greedily husbanding little green aphids for the honeydew they secrete. Yes, it could be that mankind has yet to be born. Ah, what bitter tears God must weep at the sight of the things that men do to other men!” He broke off then and I saw him shake his head convulsively, his voice a sudden cry: “In the name of money! Money!”

“I had now reached that phase of the disorder where all sense of hope had vanished, along with the idea of a futurity; my brain, in thrall to its outlaw hormones, had become less an organ of thought than an instrument registering, minute by minute, varying degrees of its own suffering.”