"I can't explain this. I don't know what would make a young man at 21 get so sick and twisted to kill nine people in a church; this is beyond my understanding... There are real people out there who are organized to kill people in religion and based on race. But it's 2015 there are people out there looking for Christians to kill them. So this is a mean time we live in."

“I'm not a libertarian. If you are, you're welcome to vote for me and help this party, but we're not gonna build the party around libertarian ideas.”

“If you killed Ted Cruz on the floor of the Senate, and the trial was in the Senate, nobody could convict you.”

“To young people out there, young people of color, young immigrants, this is a great state, but one thing I can say without any doubt, you can be an African American and go to the Senate but you just have to share our values. If you’re a young, African American or an immigrant, you can go anywhere in this state, you just need to be conservative, not liberal. Graham debating Jamie Harrison in Columbia, South Carolina”

“Let's just get to the political heart of the matter, No matter what you want to call it, beyond border enforcement, a lot of people, particularly on our side, don't want to have a debate about this. Even if you debate it, you're wrong. Even if you're open-minded about compromise, you're wrong. It's a very simple answer to a complex problem. Send them all back. End of discussion, end of debate. Now that to me is not a realistic approach to a real problem.”

“I am running because I think the world is falling apart.”

“I want you to use my words against me. If there’s a Republican president in 2016 and a vacancy occurs in the last year of the first term, you can say, “Lindsey Graham said, ‘Let’s let the next president, whoever it might be, make that nomination,’” and you could use my words against me, and you’d be absolutely right.”