"Drug misuse is not a disease, it is a decision, like the decision to step out in front of a moving car. You would call that not a disease but an error in judgement. When a bunch of people begin to do it, it is a social error, a life-style. In this particular life-style the motto is “Be happy now because tomorrow you are dying,” but the dying begins almost at once, and the happiness is a memory."

“Crazy people do not apply the principle of scientific parsimony... they shoot for the baroque.”

“told us about our own world. This, what's around us now. He wants us to see it for what it is. And I do, and more so each moment.”

“You don't go by odds. You know what's coming. You've seen the cards already." She studied his face intently. "No, you can't be cold-decked. It wouldn't be possible.”

“Silence. It flashed from the woodwork and the walls; it smote him with an awful, total power, as if generated by a vast mill. It rose from the floor, up out of the tattered gray wall-to-wall carpeting. It unleashed itself from the broken and semi-broken appliances in the kitchen, the dead machines which hadn’t worked in all the time Isidore had lived here. From the useless pole lamp in the living room it oozed out, meshing with the empty and wordless descent of itself from the fly-specked ceiling. It managed in fact to emerge from every object within his range of vision, as if it—the silence—meant to supplant all things tangible. Hence it assailed not only his ears but his eyes; as he stood by the inert TV set he experienced the silence as visible and, in its own way, alive. Alive! He had often felt its austere approach before; when it came it burst in without subtlety, evidently unable to wait. The silence of the world could not rein back its greed. Not any longer. Not when it had virtually won.”

“We do not have an ideal world, such as we would like, where morality is easy because cognition is easy. Where one can do right with no effort because he can detect the obvious.”

“In one of the most brilliant papers in the English language Hume made it clear that what we speak of as 'causality' is nothing more than the phenomenon of repetition. When we mix sulphur with saltpeter and charcoal we always get gunpowder. This is true of every event subsumed by a causal law — in other words, everything which can be called scientific knowledge. "It is custom which rules," Hume said, and in that one sentence undermined both science and philosophy.”