"One can even conjecture that Lisp owes its survival specifically to the fact that its programs are lists, which everyone, including me, has regarded as a disadvantage."

“Quotes at John McCarthy's new website maintained by Project JMC.”

“is or should be our main scientific activity — studying the structure of information and the structure of problem solving processes independently of applications and independently of its realization in animals or humans.”

“LISP is now the second oldest programming language in present widespread use ... Its core occupies some kind of local optimum in the space of programming languages given that static friction discourages purely notational changes. Recursive use of conditional expressions, representation of symbolic information externally by lists and internally by list structure, and representation of program in the same way will probably have a very long life.”

“He who refuses to do arithmetic is doomed to talk nonsense.”

“Machines as simple as thermostats can be said to have beliefs, and having beliefs seems to be a characteristic of most machines capable of problem solving performance. However, the machines mankind has so far found it useful to construct rarely have beliefs about beliefs, although such beliefs will be needed by computer programs that reason about what knowledge they lack and where to get it. Mental qualities peculiar to human-like motivational structures , such as love and hate, will not be required for intelligent behavior, but we could probably program computers to exhibit them if we wanted to, because our common sense notions about them translate readily into certain program and data structures. Still other mental qualities, e.g. humor and appreciation of beauty, seem much harder to model.”

“It's difficult to be rigorous about whether a machine really 'knows', 'thinks', etc., because we're hard put to define these things. We understand human mental processes only slightly better than a fish understands swimming.”