"If you are going to be scientistic, you will have to be comfortable with a certain amount of nihilism."

“Here is a list of some of the questions and their short answers The interesting thing is to recognize how totally unavoidable they are, provided you place your confidence in science to provide the answers”

“Science can explain why we value things, but the same goes for values we reject as wrong. That's why scientific explanations of what we value cannot justify those values or serve as a basis to enforce them on others. Since science is the only possible source of justification, if it doesn't work to justify values, nothing does.”

“Why is there anything at all? or as the question is famously put, Why is there something rather than nothing? Physics, especially quantum physics, shows that the correct answer to this question is: No reason, no reason at all.”

“There is, however, a much more convincing argument that needs to be put on the table before we really begin turning common sense upside down. It is the overwhelming reason to prefer science to ordinary beliefs, common sense, and direct experience. Science is just common sense continually improving itself, rebuilding itself, until it is no longer recognizable as common sense. It is easy to miss this fact about science without studying a lot of history of science—and not the stories about science, but the succession of actual scientific theories and how common sense was both their mother and their midwife.”

“The parts of science that rule out theism are firmly fixed. Finally, it's not just probable that God doesn't exist. For scientism, it's as close to a sure thing as science can get.”

“Physics is by no means "finished". But the part of it that explains almost everything in the universe—including us—is finished, and much of it has been finished for a century or more. This includes the physics that we are going to need. Nothing at the unsettled frontiers of physics challenges the parts we're going to make use of. What's more, the physics we need is easy to understand, certainly far easier than quantum mechanics, general relativity, or string theory.”