"I have visited both extremes on the psychedelic continuum. The positive experiences were more sublime than I could have ever imagined or than I can now faithfully recall. These chemicals disclose layers of beauty that art is powerless to capture and for which the beauty of Nature herself is a mere simulacrum. It is one thing to be awestruck by the sight of a giant redwood and to be amazed at the details of its history and underlying biology. It is quite another to spend an apparent eternity in egoless communion with it. Positive psychedelic experiences often reveal how wondrously at ease in the universe a human being can be—and for most of us, normal waking consciousness does not offer so much as a glimmer of these deeper possibilities... But as the peaks are high, the valleys are deep. My “bad trips” were, without question, the most harrowing hours I have ever suffered—and they make the notion of hell, as a metaphor if not a destination, seem perfectly apt."

“Needless to say, if I knew my daughter would eventually develop a fondness for methamphetamine or crack cocaine, I might never sleep again. But if she does not try a psychedelic like psilocybin or LSD at least once in her adult life, I will worry that she may have missed one of the most important rites of passage a human being can experience.”

“Happiness and suffering, however extreme, are mental events. The mind depends upon the body, and the body upon the world, but everything good or bad that happens in your life must appear in consciousness to matter. This fact offers ample opportunity to make the best of bad situations—changing your perception of the world is often as good as changing the world—but it also allows a person to be miserable even when all the material and social conditions for happiness have been met. During the normal course of events, your mind will determine the quality of your life.”

“Honesty is a gift we can give to others. It is also a source of power and an engine of simplicity. Knowing that we will attempt to tell the truth, whatever the circumstances, leaves us with little to prepare for. We can simply be ourselves.”

“The connection between facts and values is straightforward and philosophically uninteresting... values reduce to facts about the well-being of conscious creatures; the well-being of conscious creatures is what can be valued in this universe... Now, here’s the one bit of philosophy I’m going to anchor this to: imagine a universe in which every conscious creature suffers as much as it can for as long as it can – I call this the worst possible misery for everyone. The worst possible misery for everyone is bad. If the word bad is to mean anything, surely it applies to the worst possible misery for everyone... the moment you grant me that the worst possible misery for everyone is bad and therefore worth avoiding... well then you have every other possible constellation of conscious experience which, by definition, is better. So you have this continuum here of states of consciousness and given that consciousness is related to the way the universe is, it’s constrained by the laws of nature in some way, there are going to be right and wrong ways to move along this continuum... now this is, in philosophy, a somewhat controversial statement. I do not see how.”

“I think it should be like getting a pilot's license. I think you should require training to get a license to have a gun.”

“If premarital sex is a sin, who is the victim?”