"Drugs steal away so much. They take and take, until finally every time a drug goes into a child, something else is forced out — like love and hope and trust and confidence. Drugs take away the dream from every child's heart and replace it with a nightmare, and it's time we in America stand up and replace those dreams. Each of us has to put our principles and consciences on the line, whether in social settings or in the workplace, to set forth solid standards and stick to them. There's no moral middle ground. Indifference is not an option. We want you to help us create an outspoken intolerance for drug use. For the sake of our children, I implore each of you to be unyielding and inflexible in your opposition to drugs."

“Someone asked me if I wanted to make a New Year’s wish, and I said yes — and it was that I’d like to see every young person in the world join the "Just Say No" to drugs club. Well, just the fact that Congress has proclaimed "Just Say No Week" and in light of all the activities taking place, it seems that my wish is well on its way to coming true.”

“I am a big believer that you have to nourish any relationship. I am still very much a part of my friends' lives and they are very much a part of my life. A First Lady who does not have this source of strength and comfort can lose perspective and become isolated.”

“Our relationship is very special. We were very much in love and still are. Thank God we found each other. When I say my life began with Ronnie, well, it's true. It did. Forty-six years? Can't imagine life without him.”

“I don't intend for this to take on a political tone. I'm just here for the drugs.”

“For 5 years I've been traveling across the country — learning and listening. And one of the most hopeful signs I've seen is the building of an essential, new awareness of how terrible and threatening drug abuse is to our society. This was one of the main purposes when I started, so of course it makes me happy that that's been accomplished. But each time I meet with someone new or receive another letter from a troubled person on drugs, I yearn to find a way to help share the message that cries out from them.”

“As a mother, I've always thought of September as a special month, a time when we bundled our children off to school, to the warmth of an environment in which they could fulfill the promise and hope in those restless minds. But so much has happened over these last years, so much to shake the foundations of all that we know and all that we believe in. Today there's a drug and alcohol abuse epidemic in this country, and no one is safe from it — not you, not me, and certainly not our children, because this epidemic has their names written on it. Many of you may be thinking: "Well, drugs don't concern me." But it does concern you. It concerns us all because of the way it tears at our lives and because it's aimed at destroying the brightness and life of the sons and daughters of the United States.”