"It from bit symbolizes the idea that every item of the physical world has at bottom — at a very deep bottom, in most instances — an immaterial source and explanation; that which we call reality arises in the last analysis from the posing of yes-no questions and the resistering of equipment-evoked responses; in short, that all things physical are information-theoretic in origin and that this is a participatory universe."

“I had the good fortune of having my first and only heart attack last January ... I call it good fortune because it taught me that there's a limited amount of time left and I better concentrate on one thing: How come existence? How come the quantum? Maybe those questions sound too philosophical, but maybe philosophy is too important to be left to the philosophers.”

“Today I think we are beginning to suspect that man is not a tiny cog that doesn’t really make much difference to the running of the huge machine, but rather that there is a much more intimate tie between man and the universe than we heretofore suspected…The physical world is in some deep sense tied to the human being.”

“The question is—what is the question?”

“The best way to learn something is to have to teach it.”

“We are participators in bringing into being not only the near and here but the far away and long ago. We are in this sense, participators in bringing about something of the universe in the distant past and if we have one explanation for what's happening in the distant past why should we need more?”

“Of all obstacles to a thoroughly penetrating account of existence, none looms up more dismayingly than “time.” Explain time? Not without explaining existence. Explain existence? Not without explaining time. To uncover the deep and hidden connection between time and existence, to close on itself our quartet of questions, is a task for the future.”