"It is characteristic of the design of scientific research that exquisite attention is devoted to methodological problems that can be solved, while the pretense is made that the ones that cannot be solved are really nothing to worry about. On the one hand, biologists will apply the most critical and demanding canons of evidence in the design of measuring instruments or in the procedure for taking an unbiased samples of organisms to be tested, but when asked whether the conditions in the laboratory are likely to be relevant to the situation in nature, they will provide a hand-waving intuitive argument filled with unsubstantiated guesses and prejudices because, in the end, that is all they can do."

“The great attraction of cultural anthropology in the past was precisely that it seemed to offer such a richness of independent natural experiments; but unfortunately it is now clear that there has been a great deal of historical continuity and exchange among those "independent" experiments, most of which have felt the strong effect of contact with societies organized as modern states. More important, there has never been a human society with unlimited resources, of three sexes, or the power to read other people's minds, or to be transported great distances at the speed of light. How then are we to know the effect on human social organization and history of the need to scrabble for a living, or of the existence of males and females, or of the power to make our tongues drop manna and so to make the worse appear the better reason? A solution to the epistemological impotence of social theory has been to create a literature of imagination and logic in which the consequences of radical alterations in the conditions of human existence are deduced. It is the literature of science fiction. … cience fiction is the laboratory in which extraordinary social conditions, never possible in actuality, are used to illumine the social and historical norm. … Science fiction stories are the Gedanken experiments of social science.”

“Lysenkoism is held up by bourgeois commentators as the supreme demonstration that conscious ideology cannot inform scientific practice and that "ideology has no place in science." On the other hand, some writers are even now maintaining a Lysenkoist position because they believe that the principles of dialectical materialism contradict the claims of genetics. Both of these claims stem from a vulgarisation of Marxist philosophy through deliberate hostility, in the first case, or ignorance, in the second. Nothing in Marx, Lenin or Mao contradicts the particular physical facts and processes of a particular set of natural phenomena in the objective world, because what they wrote about nature was at a high level of abstraction. The error of the Lysenkoist claim arises from attempting to apply a dialectical analysis of physical problems from the wrong end. Dialectical materialism is not, and has never been, a programmatic method for solving particular physical problems. Rather, dialectical analysis provides an overview and a set of warning signs against particular forms of dogmatism and narrowness of thought. It tells us, "Remember that history may leave an important trace. Remember that being and becoming are dual aspects of nature. Remember that conditions change and that the conditions necessary to the initiation of some process may be destroyed by the process itself. Remember to pay attention to real objects in space and time and not lose them utterly in idealized abstractions. Remember that qualitative effects of context and interaction may be lost when phenomena are isolated." And above all else, "Remember that all the other caveats are only reminders and warning signs whose application to different circumstances of the real world is contingent.”

“he psychic and physical characteristics of human beings, and the differences between individuals, are the consequence of an interaction between the genes that are present in the fertilized egg and the sequence of environmental circumstances that the developing organism experiences during its entire life history. With a few exceptions, like cystic fibrosis where possession of the defective genotype leads ineluctably to the disease, or language acquisition where the language spoken depends only on experience and not at all on genotype, human characteristics are all subject to this interaction of forces. There are, moreover, random events in cell growth and differentiation that are neither genetic nor environmental in the usual sense, and which play an extremely important part in development, especially in behavioral traits.”

“To say that genetic differences are relevant to hetero- and homosexuality is not, however, to say that there are “genes for homosexuality” or even that there is a “genetic tendency to homosexuality.” This critical point can be illustrated by an example I owe to the philosopher of science, Elliott Sober. If we look at the chromosomes of people who knit and those who do not, we will find that with few exceptions, knitters have two X chromosomes, while people with one X and one Y chromosome almost never knit. Yet it would be absurd to say that we had discovered genes for knitting. The possession of two X chromosomes causes an embryo, with rare exceptions, to develop into an anatomical and physiological female, while the possession of a Y chromosome leads almost always to male development, and in our culture women are taught to knit while men are not. The beauty of this example is its historical contingency. Had we made the observations before the end of the eighteenth century , the result would have been reversed. Hand knitting was men’s work before the introduction of knitting machines around 1790, and was turned into a female domestic occupation only when mechanization made it economically marginal.”

“Genetics is the study of similarity between relatives, and the problem of human genetics is that, in a species with a family and social structure and a taboo against manipulating individual life histories experimentally, there is a confounding between the similarity of relatives that arises from biological causes and the similarity that arise from social causes.”

“The social scientist is in a difficult, if not impossible position. On the one hand there is the temptation to see all of society as one's autobiography writ large, surely not the path to general truth. On the other, there is the attempt to be general and objective by pretending that one knows nothing about the experience of being human, forcing the investigator to pretend that people usually know and tell the truth about important issues, when we all know from our lives how impossible that is. How, then, can there be a "social science"? The answer, surely, is to be less ambitious and stop trying to make sociology into a natural science although it is, indeed, the study of natural objects. There are some things in the world that we will never know and many that we will never know exactly. Each domain of phenomena has its characteristic grain of knowability. Biology is not physics, because organisms are such complex physical objects, and sociology is not biology because human societies are made by self-conscious organisms. By pretending to a kind of knowledge that it cannot achieve, social science can only engender the scorn of natural scientists and the cynicism of the humanists.”